What is Ass-and-mouth Disease?
Essentially the inability to control one's bowels from both openings (mouth and anus) simultaneously. Usually brought about by the ingestion of improperly prepared food containing harmful bacteria or allergens.
Dave: Did you hear what happened to Steiny out in India?
Josh: Yeah, he shat and barfed all over his bed after he caught ass-and-mouth disease from that street vendor!