What is Bust It Up?
1.
to have a good time; party
"Let's all go over to Jake's house party and bust it up with the honeys there!"
See
2.
smash an ecstacy pill to parachute or snort it
Gimme a pill man I'm gonna bust it up and rail it.
3.
talk for a long time
me and the jawn bust it up. Now i know I errythin about her.