What is Calmette?
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A "calmette" is a person who is new or inexperienced in a subject, usually an online dating site. Calmettes are usually annoying and excessively stupid. Do not confuse calmettes with calvins, who are inexperienced people that tend to be more mature and strive to become better.
Guy: If I could rearrange the alphabet, I'd put U and I together.
Girl: Ew gtfo you calmette.
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an overall an overall sucumbing of shitnessnisity
wow niccolo, you really have a bad case of God Cancer, your right nut is missing
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