What is Calvin Klein?
1.
Doing lines or bumps of coke and ketamine at the same time
user1: Who wants to Calvin Klein?!
user2: I do, I do!!!
user3: You betta werk bitch! CK'ing is fierce!!
See
2.
A drug slang term used to describe a cociane and ketamine combination. The term originated from the new york dance scene back in the day.
They got super messed up on a calvin klein combo.
See