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House, MD fans often say this to express excitement, fear, panic, etc.
Used the same way "Oh My God" is used.
Fan #1: "..
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Having the tendency to scream profanities at other drivers who are talking on their cell phones, futzing with their I-Pods or doing ever..
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combination of performing the "flying V" with a sexual partner of choice while keeping under garments, right before coitus end..