What is I-factor?
1.
The perpetual and unfailing insanity ("i") of females of all ages, races, creeds, colors, religions, sexual orientations, and other dispositional differentiators, without exception.
"Man, 100% of girls are just crazy. Every last one of them, I swear."
"Dealin' with some of that i-factor lately?"
See
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With Out No K.Y. When you don't have any lubricant for butt-sex, but you decide to do it anyway.
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