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1. nasticate-to make things hard for someone.. Joe - how is you gurl? Martin -she is fine, her friend Beth has been trying to nasticate m..

1. Slut, whore, Prostitute, Dumbass, has herpes and AIDS- and fuckin genital worts. She has fucked every guy I KNOW. Fucking nappy hoe..

1. A general purpose insult. A little stronger than something like "you piece of shit!" Unique to the South. (After an argumen..