Mister Sister

What is Mister Sister?

A drag queen.

Origin: "Will and Grace"

Don't mess with that mister sister, or you'll end up looking like a Cher barbie doll gone bad.

See drag queen, jack, cher, asdfghjkl

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Humpledorf

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Homotrannycat

1. A very offending insult, meaning that the person who the insult is directed to is a pussyand unsure of their sexuality "Oh my god,..

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Mister Sister Edit Meaning