What is Oh Noes!?
1.
Variant of "Oh no!", used sarcastically to indicate that what is being referred to is NOT, in fact, something to be alarmed about.
"My World of Warcraft server's economy is ruined! I can now only sell Arcane Crystals for 7 gold coins apiece, whereas before I could sell them for 8."
"Oh noes!"
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2.
When you are royally fucked.
3 little girls are on a tube ride in their local lake. They hit a monster wave, and all 3 of them fly off of the rub screaming oh noes!
3.
1) A response to a negative situation which is insignificant, or at worst, a temporay inconvenience.
2) A response to a negative situation occurs on a regular basis, to the point where it is expected.
Guy A: "Aw, man, the Marlins lost"
Guy B: "Oh noes!"
Guy A: "Windows crashed again."
Guy B: "Oh noes!"
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4.
The expression, gesture or sound of someone's sexyness or misfortune.
Oh Noes! He is sexier than me.
Oh Noes! I am a sexy beast.