What is One For The Big Girls!?
1.
A scream/cheer for when a "big-boned"/
"One for the big girls!" was what Bertha screamed as she watched Dr. Callie Torres get it on with
McSteamy inGrey's Anatomy
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7.
(v.i.) Out to lunch; not having it together; acting in a stupid way. Typically derogatory.
Derivation: ..