What is Powerpuff?
1.
puff, puff, PUFF. pass.
dat guushyyt: wait, is it puff, or puff puff?
juicy shyyt: nigga it's powerpuff!
dat guushyyt: hell yea
See
2.
A preppy, girly person.
A Powerpuff walked by wearing a mini purse.
See
3.
Awesome, a most richeous thing, cool, mondo, da bomb, just so damn powerpuff!
Dude, that is just so powerpuff.
See