What is Stackers?
1.
1- pharmaceutical uppers, stimulants, or steroids
2- Easy method of measuring and transporting street drugs in pill form.
1- I was dragging ass today at work, so I popped a couple of stackers and now I'm a hummingbird
2- I got some stackers of X mixed with coke... where'd I leave that fucking razor?
2.
That annoying arcade game you see at 
Crap! I just spent $10 at stackers and all I got was a lousy hippo keychain.
See 
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