Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Ylif

1. Your Life Is Fucked. Made popular by the site FMyLife. Usually said in agreement with someone who thinks their life is fucked. "My..

Oral Constipation

1. when someone who is usually full of words and useless sayings is suddenly put on the spot, and can't find shit to say. A lack of w..

You Have Fun With That

1. if you have a friend, and they do or have to go to something that you arent interested in.. you say "you have fun with that" ..

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Three On The 21 Edit Meaning