Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Iceblock

1. Having (or nearly having) a sexual escapade interrupted by intrusion (physical or otherwise) by one of one's geeky internet friends..

Hamster Party

1. When a bunch of homosexuals buy some hamsters and some tubes, and then bring them home to stick the tubes up their anal holes. They then..

J00r Mother

1. bastard woman from hell in a toilet seawtcvgf tnuymr..

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Three On The 21 Edit Meaning