Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Orgasmic Spody

1. The act of having sexual intercourse upon a toilet filled to the brim with urine, feces, menses, vomit, cum, and used condoms without ge..

Yellabone

1. A man with a severely swollen penis; a well endowed asian male "Have you seen Mr. Lam? That's one ill yellabone!"..

Zindizzle

1. zindizzle is a girl on da da vizzle collizzle in leidizzle she is 16 years old and she is a very nice girl 1. Without izzle: Have you ..

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Three On The 21 Edit Meaning