Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Bufu Buddies

1. two homosexual males who are involved in occasional anal sex "yo raven and that other fag are bufu buddies"..

Elastic Pipeline

1. When a male dumps into a condom and then freezes it. then uses it as a dildo on a female. baby, lets take the elastic pipeline out of t..

The Thorton

1. The tiny patch of hair a woman will leave unshaven right above the clit. Resembles the small patch of hair below the lip of Billy Bob T..

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Three On The 21 Edit Meaning