Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Ellisse

1. a pretentious art student who is very self centered and shallow. she is 24 times hotter than anyone you know. ellisse only paints portr..

Zalman

1. a guy wearing his shorts rediculously. Zalman, he's got shorts reaching his knees..

2pak

1. Extreme newbie0r. Thinks his spare video cards are "1337" Trys hard with his server computers that have no purpose. Likes t..

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Three On The 21 Edit Meaning