Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Lysh

1. A nickname that Alyshagave to herself in Freshman year by dropping the A's in her name. Figuring if she never got any A's in h..

Hotdog Spoon

1. The act of placing your penis so that it rests gently between the butt cheeks of another, male of female, while at no time achieving pen..

Chicken Tender Sub

1. n.- refers to a man over 40 years old who is sexually appealing to younger females. I know she is my best friend, but her dad is such a..

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Three On The 21 Edit Meaning