Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Ze Buttfack

1. Literally means "the buttfuck", or anal sex, sodomy, etc. Spoken in a French accent Vould yoo like ze buttfack, monsieur? 2..

Hajeema

1. "Stop it!" And we owe this all to Kat, the creator. Sandra:Your mom's chest hair! Katerina:Hajeema!..

Nubcaek

1. A jesty way to call someone a newbie. Correct misspelling of "newbie cake". Uber nubcaeks occassionally type it as "nubc..

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Three On The 21 Edit Meaning