Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Day-em

1. Damn, just saying it with a strange accent. "Day-em thas fresh crazy mofo!" See id..

Popolopas

1. Bitch Ass Pussy. Term Originated in Puerto Penasco, Mexico in the Spring of 2008. Masculine: Popolopos Feminine: Popolopas That ATV ..

Reamer Club

1. An organization of unembarrassable Purdue University students that promotes school spirit, embraces the school's traditions, and ca..

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Three On The 21 Edit Meaning