Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Nut-buttered

1. when someone puts their hand down their pants then smacks someone (this term originated from SW Pennsylvania) your mom:why did you hit..

Irratted

1. A mix between being irritated and agitated. A major feeling of agitation. Sometimes synonymous with the feeling you get with growing pai..

W/u

1. With You, I Would Never Break Up w/u Why Did Yu Break Up w/me? See with, me, you, break up..

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Three On The 21 Edit Meaning