Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Esson

1. a kiddy fiddling man molester I say Charles, that fellow over there is behaving like a right Esson...

Truvie

1. a large clay vessel for carrying water in Siberia Lena poured water out of the truvie after coming back from the well. See truvie, wat..

Hobbledehoy

1. An awkward, gawky young fellow. And there he stood, his hobbledehoy frame clashing with the elegence of the room. Steve Nash? I bet..

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Three On The 21 Edit Meaning