Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Icon Cow

1. Celebrities who overestimate their talent and are given too much money and promotion. Ayumi Hamasaki, the so-called Queen of Japanese P..

Jobonee

1. Anyone who has a JOB (just over broke) as opposed to an entrepreneur. "Honey, don't get mad...that fellow is just a jobonee.&..

Homojuice

1. Cum or sperm ejaculated from one man onto another man, usually through oral fixation. His homojuice made me so horny. See gayjuice, Ge..

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Three On The 21 Edit Meaning