Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Ring Around The Rosy

1. The red rind around your penis when you remove a tight condom. The condom was so small it gave me a Ring Around The Rosy . See condom,..

Going Retarded

1. Going commando (without underwear) while wearing jeans. Which is a really stupid thing to do, because jeans are tight and stiff and rou..

Fuck It, Bro!

1. A strategy for making everyday life decisions that may be dangerous, illegal, or capable of hurting another's feelings, for example..

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Three On The 21 Edit Meaning