Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

To Mook

1. To act in a stupid, futile, or otherwise misguided fashion. He had a chance of hooking up with the gal until he mooked it up by spillin..

Knuckles Christmas

1. When a girl you like, is fucken with your feelings w0w christina is totally fucken up wit knuckles christmas See player..

Narcore

1. knarly and hardcore put together Holy fuck that dude is narcore! See narcore, knarcore, knarly, narly, hardcore..

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Three On The 21 Edit Meaning