Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Black Angel

1. 1. One who plays online games in a manner that instills both fear and respect into those he plays against and with. 2. The opposite of ..

Oizu

1. 1. short for "oi oi, you." the pluralized form of "oi" shortens into "ois", which is further changed to &q..

Frontanus

1. Big nasty fat ass that has a fupa which folds back in in the front making it look like an ass on the front of the body, hence the front..

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Three On The 21 Edit Meaning