Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Hung-sorefeet

1. The darling of CEPR. Miss Sore feet can be found sleeping in the lobby at CEPR, or in the EOC having here feet rubbed dwon by Linda. O..

Ho Squad

1. A group of three or more girls that are ho's or act hoish, for example wearing ho like clothes, with their big o titties hanging ou..

Enbody

1. A homeless person who failed at life. Usually found on highway entrance ramps with signs written in ketchup(catsup). "Dude, did yo..

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Three On The 21 Edit Meaning