Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Clod Hopper

1. farmercowboyhickrural person A person who has to walk over plowed fields to get somewhere. Gee, the way Frank is dressed, lools like a..

Lulzcake

1. The act of chocking on your own lolz, comes with the option of being with frosting. John: Hey look Tim is chocking on a piece of lulzca..

The Rahn Choke

1. While getting head you jam your cock into the back of the girls throat with the intent of having her puke on your dick and continue to f..

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Three On The 21 Edit Meaning