Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Buckatoo

1. Also Known As Bukkake Several men cumming on the face of one woman. Messy Times! "Oh I saw this video on the internet last night..

Zootie

1. A joint laced with crack. pass the zootie See AC 2. Phencyclidine - aka PCP or "Angel Dust". Can be used to refer to other..

Incesbian

1. a female who participates in a sexual relationship with another female relative (sister, cousin). no one in the family quite knew how t..

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Three On The 21 Edit Meaning