Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Youduke

1. When party disintigrates because someone starts showing youtube clips and then another person has to show some other clip and so on. Bef..

Joe*

1. To get slapped in the face by a condom. The condom being either used or unused, filled or unfilled with any substance whatsoever. Joe ..

Your Mummy's Bum Cunny

1. your mother's arsehole I was thinking earlier about poking a bit of cat shitinto your mummy's bum cunny. See arse, poohole, ..

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Three On The 21 Edit Meaning