Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Anal Clown

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Ihorpwafas

1. International House of Reasonally Priced Water and Fries and Stuff. Originally from Hannah Montana, now used as a synonym for a non-exi..

Konjohn

1. an Asian kid that plays games alot he takes the first word of his screen name and combines it wit his name ayo where konjohn at?? foo..

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Three On The 21 Edit Meaning