Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Fire One Off The Cuff

1. To masturbate (male) My bitch wasn't around and I was hornier than a dog with two dicks, so I quickly fired one off the cuff befor..

Twat O'clock

1. an undesirable time of the day. "that fucking fire alarm woke me up at twat o'clock this morning!" See twat, time, morn..

Querty

1. a cross between "queer" and "flirty" Considering his querty way of dealing with his students, I'm surprised he..

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Three On The 21 Edit Meaning