Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Dillian

1. gets lots of blow jobs, likes abbeys, and smokes a lot of weed. usually a pretty cute guy. shit man, that dillian is always getting a b..

Microwave Broccoli

1. A euphemism for a fartthat is extremely offensive to one's sense of smell. Derived from the smell of broccoli being re-heated in a ..

Suburbanegro

1. An African-American that lives in the suburbs, or a mostly white-populated town. Could also be considered the exact opposite of the ghet..

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Three On The 21 Edit Meaning