Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Droolmaster

1. Someone who is experienced in the art of public drooling. All hail the droolmaster! See drooler, spit, master..

Queezin

1. its when a thug like kyle schmelig straight shoots u in da face. holla. look playa, kschmel's straight queezin dat foo! 1. its w..

Mule-eye

1. The phenomenon that results from being surrounded by an overwhelming majority of mediocre looking women, whereby "6.5's" ..

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Three On The 21 Edit Meaning