Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Cunt-o-rama

1. when there are 5 or more chicks lying in their back with their legs up waiting fo ryou to fuck them all at once Last night at the club ..

Eh Eh Eh

1. The phrase which TV legend Anne uses on 'Little Britain'. Man: "No, Anne! That's Emma's Gerbil! Don't thr..

Yeppernoodle Soup

1. A confirmation of a statement which has nothing to do with soup. Usually used in cheery situations. Bob- "Did you get that homewor..

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Three On The 21 Edit Meaning