Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Paigegasm

1. when you have alot of tension built up for just this one person (it can be sexual tension, or just anger), && finally when you j..

Droiers

1. what white people call underwear, and or boxers Boy, did you shit your droiers just then? See shit, underwear, boxers, white people..

Nard-hound

1. one who likes to be around balls. at first you might think the person just admires your personality and wit but eventually you will fin..

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Three On The 21 Edit Meaning