Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Mtuah

1. --mom that's ugly as hell. opposite of a milf. Kenny-"Man did you see Jen and Becky's moms?!" John-"Yeah dude..

Nigger The Shit Out Of

1. 1) to take advantage of, especially to over-consume one's share of something that is available to only a small group of people 2) ..

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1. Pooping back and forth, as described in the movie "You and Me and Everyone We Know". "I'll poop into your butt hole..

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Three On The 21 Edit Meaning