Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Great Head

1. To get extremely good fellatio/head I got such great head last nite, I woke up this morning and had to pull the drapes out of my ass!..

Knackerized

1. to get a good kicking or telling off from ones parents as a child. eg "oh no im nearly 3 hours late i should of been in at 9 im go..

Quafia

1. a mafia of females all farting from inside their vagina do you hear that quafia over there? god that stinks See quaf, quife, queaf 1...

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Three On The 21 Edit Meaning