Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Memphis Mudslide

1. When one attempts to deliver a Boston Pancake only to discover that they have diarrhea. Dude, my chick was totally down for a Boston Pa..

Zuper

1. Adj.: Means extremely super. Came from the word super. Pronounced: Z'oo'per Thats zuper cool. Yeah dude, that's sicky ..

Knob Nuggler

1. When someone has anal-sex with more then ten people in one night. However, each person that gets laid that night (except for the one who..

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Three On The 21 Edit Meaning