Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Shaima

1. A totally beautiful girl. That girl is such a shaima! See coolness 2. enjoys good coffee, peppermint tea, mountain dew, and clementi..

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Hoogaboogood

1. When a man ejaculates on his own knee and slams it into the nose of his female companion. Jerry hoogaboogood all over the face of Jonna..

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Three On The 21 Edit Meaning