Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Zeiner

1. sweaty pitted ugly skank, who thinks theyre a pro craka basketball playa or somethin you look like a zeiner! and you have body odor. S..

Burundi

1. I little country in mid-Africa, South of Rwanda, Capital: Bujumbura, Pop: >6,000,000 (the country) Ethnic tensions between the H..

Porkloaf

1. A very sloppy pussy that you can fit your head it and more. **See LP** "I stuck my foot in that porkloaf last night"..

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Three On The 21 Edit Meaning