Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Queen Of Cream

1. A term for a sexually promiscuous and indiscriminate women, esp. in the areas of taking penises' hot wads in her mouth. Don't..

Bitch-horn

1. Clitoris. Female fun part. Lady Skanksalot said to her enemy, "You can just lick my bitch-horn!" See clit, clitoris, cock, ..

Vanilla Mudslide

1. A messy facial that is delivered upon an "individual" by six or more men. This started out as a woman but changed to individu..

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Three On The 21 Edit Meaning