Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

John Deer

1. take anal beads and put them up a girls ass then proceed to put your foot on her ass and pull them out like a pullstart on a tractor. d..

W00tw00t

1. Statement made by a g33kwho is really excited or thrilled. So thrilled that one w00t simply isn't enough. Uber w00tw00t! See w00t..

Zipcon

1. The home planet of a species that are currently invading the planet Earth. see also motherboard We are here from Zipcon...

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Three On The 21 Edit Meaning