Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Holly Madison

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Cincinnati Car Bomb

1. The act of taking a dump inside of a car. When I saw that decrepit geezer rolling across the parking lot laughing devilishly, I realize..

Apple Iphone

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Three On The 21 Edit Meaning