Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

G-parkway

1. in South Sacramento..always gon be G-PARKWAY, aka shining star or Franklin Villa (pale face boys keep tryna change tha name), hood in sa..

Zegia

1. person that have a lot of sex with a lot of people almost like twice a week with different men and women Also known as a slut, whore an..

Freak In The Sheets

1. A girl that appears prim and proper until you get her in bed where she reveals her true insatiable craving for hot, wild, relentless sex..

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Three On The 21 Edit Meaning