Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Ltao

1. Abbv. Slang Laughed Their Asses Off Similar to LMAO but referring to a group. I told a joke that made them LTAO! See laugh, ass, laug..

Zuster

1. A foolish person. Someone who acts retarded but is not. It can also refer to a male who seems to lack a clear sexual identity, usually..

Grizzile

1. jigga talk fo yo teef platinum in grizzile..

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Three On The 21 Edit Meaning