Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Marjani

1. good in bed,weirdo,talks to herself,hottie,bangin booty i heard marjani was at Travis crib yesturday...i want to ba a marjani someday! ..

Alorn

1. A person who is extremly good at giving oral sex while brushing their teeth. Most cases involving two females. That bitch is so good at..

Leet Cheese

1. An item or thing or someone who is the most elite (or leet or 1337). Leet Cheese is the pinnacle of eliteness. The one who pwns the mos..

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Three On The 21 Edit Meaning