Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Bum-upper

1. Slang word for male homosexual Used as a noun: He is a bum-upper (or, rarely, 'bumupper') Used as a verb: He ups bums Gener..

N-16

1. 1337 speak for Nig. We have a code N-16, stay out of the halls, I repeat we have a code N-16! See nig, 1337, leet, niggar, nigga, nigs..

Pugfuggler

1. One who is stoned via Natalie Catzman OMG!!! You stole my stash, you little pugfuggler!!!!! 1. One who is stoned via Natalie Catzman ..

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Three On The 21 Edit Meaning