Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Baked Goodz

1. When a friend is a total faggort and ditches everyone he knows to chase after some skanky pussy, he has "baked goodz" This co..

On The Side

1. Having an extra sex partner. Having sex with a friend as in friend with benefitswhile in a relationship with someone else. I like fucki..

Van Pelt

1. When a girl pulls the rug out from under a guy, the way Lucy used to do with Charlie Brown Joe: "do you love me?" Jill: &quo..

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Three On The 21 Edit Meaning