Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Melldust

1. The residue left on the couch after finally fucking a fat chick She was oozing with Melldust..

Rynebrock

1. Someone who you find amazing and/or adorable. "Aren't you just a modern-day "rynebrock" " ?! See cool, party,..

Vinegar Salt

1. Ghetto way of asking for Oil & Vinegar, Salt & Pepper when ordering a sub at Subway or Publix... Sandwich Artist: "Anythin..

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Three On The 21 Edit Meaning