Three On The 21

What is Three On The 21?

In reference to Trisomy 21 where there is 3 genetic materials on the 21st chromosome instead of the usual 2. This causes Down's Syndrome.

He never really understnads what is happening.I think he's a little 3 on the 21. Started in Canada in 2004.

Cocksure

1. A condition of extreme (sometimes foolish) confidence or boldness pertainng to or having to do with the size of one's penis ("..

Kimodameshi

1. 1. test of courage (or foolishness); most often takes place at night in classic settins like abandoned houses, forests, and graveyards ..

Emo-nerd-wankster

1. A nerd guy who has a 8.0 GPA and doesn't have many friends. Likes to listen to GreenDay shit and that friendship stuff make him th..

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Three On The 21 Edit Meaning