What is Twerpy Mouse?
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n. slang 1. A playful term used to describe a small framed female who often does not think before acting, but instead, and most often, acts and reacts on pure impulse without rhyme or reason.
(as she walks directly into a bedroom wall that has been there for years,) "Robin... That wall has been there for years. Why did you just walk into it? You're such a twerpy mouse."
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What cool dudes say when someone's being a noob.
Noob: *spams up the boards*
Cool dude: Wow. You fail at the internets...