What is Twis?
1.
Twis means to be under the influence of either drink or drugs
"i'm gunna get twis 2nyt"
"man iz twis"
See
2.
Internet shorthand for "that's what I'm saying."
Meaning the person wholeheartedly agrees with the concept of the previous statement.
see
> He's gotten heavy.
> He needs to get his ass to the gym.
> twis!
See