What is Upsyndrome?
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1. The state of one's PENIS being in a perpetual state of happiness.
"Ever since meeting Caroline, I think Tom has come down with a bout of up-syndrome."
"...It really sucks having your upsyndrome flair up at a gay bar..."
We always thought Susie was weird, then the truth reared its ugly little head -- out of her pants when she was diagnosed with up-syndrome!"
5:00 News Headline:
"Rare condition found in man with up-syndrome -- are two penises better than one?"
Random Words:
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1) A girl that is disgustingly overweight, a slut, and has a wide-set vagina.
2) A large proscious black girl who cums from the jungle...
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One who climaxes without making any noise.
I was with Sherwin last night, and I didn't even realise he came. He's a real quie..