Upsyndrome

What is Upsyndrome?

1. The state of one's PENIS being in a perpetual state of happiness.

"Ever since meeting Caroline, I think Tom has come down with a bout of up-syndrome."

"...It really sucks having your upsyndrome flair up at a gay bar..."

We always thought Susie was weird, then the truth reared its ugly little head -- out of her pants when she was diagnosed with up-syndrome!"

5:00 News Headline:

"Rare condition found in man with up-syndrome -- are two penises better than one?"

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Upsyndrome Edit Meaning