What is Upsyndrome?
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1. The state of one's PENIS being in a perpetual state of happiness.
"Ever since meeting Caroline, I think Tom has come down with a bout of up-syndrome."
"...It really sucks having your upsyndrome flair up at a gay bar..."
We always thought Susie was weird, then the truth reared its ugly little head -- out of her pants when she was diagnosed with up-syndrome!"
5:00 News Headline:
"Rare condition found in man with up-syndrome -- are two penises better than one?"
Random Words:
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What you say when there is an akward silence
(Akward Silence) Nucca Nucca Nucca..
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to release an oily water-like substance out of the anus, after consuming low to non-fat foods, such as WOW chips.
"I have to go cl..