What is Anger Up The Blood?
1.
1: to irritate so that it makes one's blood become angry.
2: to cause, by reason of stupidity, ineptitude, malice, or uncaring, the blood of another to become angry.
3: to think certain thoughts or participate in any such behaviour that would tend to cause your own blood to become angry.
"I don't read newspapers, they anger up the blood."
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When you have the intention of hooking up with someone but by the end of the night you have to settle for your second choice.
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