What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
See
Random Words:
1.
A term used to insult people, refering to homosexual nazi school girls.
Phil: Pat you suck!
Pat:Yah well, you're a nazi school fa..
1.
Forcefully yet discretely insert a medium sized gummy coated bear into the opening of a womans vagina. Using your imagination increases ..