What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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A high school outside of Denver, Colorado. Just a perfectly normal, stereotypical high school, until a couple of sickos shot up the plac..
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The city.
The term refers to its streets, alleys, subway system, inner-city neighborhoods, playgrounds and schools. Usually a metropol..
