What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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1.
It is some with a very wrinkly face that resembles a cauliflower floret.
A Cauliflower face is a wrinkly old lady who's arch nemes..
1.
used largely in the north-east of Scotland, literally meaning "what the fuck?"
"Fit the fuck you lookin' at yi bam&..
