What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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(Noun) A female spokesperson used in television advertising primarily because of her large breasts and overall sex appeal; she is usuall..
1.
When a girl is having a yeast infection, you have anal sex while she's crapping all over your man-meat
My girl was on the crapper,..
1.
Means the same thing as,wh ats going on
whats up in this piece?
See sup, what's up..
