What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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1.
a grouping of twats; collected and placed one on top of the other
Hey, check out that twat stack. it's 6 twats high.'Gotta fe..
1.
When you do something dumb you become a queer burger or if you act really stupid
Dude, stop being a queer burger or i will slap you up ..