What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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1.
General insult, non-vulgar most often used in jest.
John: You bought 25 raffle tickets, and I bought two, but I won the money!
Bill (i..
1.
When a person with normal IQ levels experiences a brief moment of mental retardation. The term was "coined" in New York.
Fake..