What is Big Louie?
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A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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Random Words:
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Loping the mule, jerking the gonaskas, whipping the wire, the old five knuckle shuffle across the ole piss pump.
After seeing his rooma..
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1. A command of two words one prepatory(about) and one of action (face) given to a soldier that is standing at the position of attention..