What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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1.
Adj. To describe the taste of food after is has been microwaved.
The sandwich has a microwavie taste.
See funky, off, unnatural, plas..
1.
when you are really sick and you sneezzze a lot
ohhhhhhh mammmmmmma im felin like shibitibin
See caugh, drool, snot, shibitibin..