What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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Random Words:
1.
when you make a loogie type snot leak from your nose until it becomes at least the size of a pack of new PENS!!
Man did you see the way..
1.
A female taking one in the poon, one in the butt, one in the mouth, and one in each hand while laying on a lazy susan so the men can spi..
