What is Big Louie?
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A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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This was invented by Kevin Denscombe. It was invented as a joke, and now is used a lot by people.
Some of Kevin's young cousions t..
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One of those posers who shops at the poser store, Hot Topic. Tends to spend hundreds of dollars on crap that you can get for a few cents..