What is Big Louie?
1.
A generic phrase to describe any sexually transmitted disease, or as a shorthand to describe having multiple STDs. Some dispute exists as to the proper spelling, but either "Big Louie" or "Big Louis" is acceptable.
Dude, if a chick ever makes you get tested for the Big Louie, make sure to piss in the cup instead of letting them stick that huge q-tip in there, that shit hurts.
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Random Words:
1.
A slutty Bitch Nigger
that ho is is a slitch nigga.
See slitch nigga, slitch, nigga, nigger, bitch..
1.
A man, who sneaks into the room of unsuspecting mothers, and does a strange ritualistic dance around them called the quibble quable. usu..
