What is I.s.?
1.
Information Systems
High School computer geeks usually go on to lucrative careers in I.S. departments.
2.
independent study
i am part of i.s.
See
3.
I stupid...me kno nothing
I.S. didn't ya kno that?
See
4.
inverse smile
i.s.
5.
Short for
Pronounced "is" not i.s.
"Yo dude, the itis is hittin' me quicktime, let's hit up I.S."
Friend 1: "Yo, ima go home and get some sleep before soccer dude."
Friend 2: "Nah, let's just hit up I.S. for a quick minute."
See
6.
The term for a man's rather large thang "Italian sausage"
"Yoo girl u want to taste some of this italian sausage?"