What is Mean Gene?
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noun: a bout of diarrhea that comes on so quickly and ferociously that one would stop at any location with a working toilet- even a Mean Gene restaurant in the middle of West Virginia.
also used to describe any horrible fecal experience
I hope that aint a mean gene comin' on because we are miles from toilet paper.
Damn dude, I just dropped a mean gene that almost made me cry.
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