What is S.i.s?
1.
Self inflicted shanks:
Stab wounds that one purposely makes usually to frame someone.
Dude 1: dude he shanked me!
Nigga 1: Naa dats just an S.I.S
dude 2: he was with me he coudlnt have done it
-dude 1 walks off angry-
See
2.
Means to "sit in silence" insetad of lol. Usually used if somebody sais something retarded online, its a good way to be honest. Lets face it very few actually laugh at stuff online.
xXihateyouxX: i was like "duhhhhhhh" haha
ay u guys 2003: s.i.s
3.
S.I.S is an acronym for Special Investigation Section.
It is an Los Angeles Police Department's elite tactical detective squad with a straightforward mandate: Track down the City’s most dangerous offenders and take them off the street. S.I.S. are possibly the hardest-working, most dedicated men and women Detectives to wear a badge.
Alonzo: Hey, Mark, where are you transferring to?
Mark: S.I.S.
Alonzo: Yeah, S.I.S. Detective.
(from 'Training Day')
See