What is Syphed Up?
1.
A person who has contracted a considerable number of sexually transmitted diseases.
A person who hits a nasty chick from the back and contracts all her diseases.
Joe: "hey man I heard you hit that nasty chick that works at Denny's"
Rob R: "Yeah I hit that shit and now I'm all syphed up"
See
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Masterbating
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1.
(v) In the world of "leet" (1337), possibly meaning to create a virus, or other highly annoying/fatal program inserted into an..