L.s.e. Edit Meaning

1.

a.k.a. Leslie. A girl with low self esteem. Primarily used in social situations when a male is looking for some female companionship and needs to fnd the path of least resistance...Usually not the prettiest (or slimmest) girl in the room. On rare occasions, the girl may be extremely attractive physically with some sort of severe emotional defect due to childhood trauma or other disorder( see Howard Stern) Cannot be used to describe dudes.

John: AYO, imma go holla at this chick in the corner by herself...She got L.S.E. written all over her lonely face.

Jack: That should be an easy piece of road beef my friend.

See uggo, jump-off, beer goggles, fubu, walk of shame